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General signs are tiredness, weight loss and mild fever. Intestinal symptoms can develop at a later stage.

Symptoms/manifestations in Crohn’s disease:
  • irregular bowel movements or diarrhoea: a common long-lasting problem that can recur several times a day; loss of fluids, vital nutrients and blood;
  • abdominal pain: usually cramps, often after eating, bloating; they occur at inflammation sites and gut areas affected by the disease;
  • fever as a response to inflammation;
  • fatigue and feeling a lack of energy;
  • weight loss due to lack of food intake or bowel dysfunction;
  • development and growth inhibition and hormonal disorders in children/adolescents;
  • anaemia: iron deficiency, vitamin B12 deficiency;
  • nausea.